Academic trials
Having sponsored more than 25 investigator-initiated multi-center trials in interventional cardiology, CoroScience are experts in navigating the increasing complexity of performing high impact independent research.
Large Network
Collaborating with more than 100 heart centers around the world, CoroScience is able to accelerate any recruitment period. We value and maintain our international collaborators by hosting both online and physical meetups at congresses, networking & "touching base". Cultivating our relations fosters future collaborations, minimizes initiation-, training- and communicative-costs, and quite simply just makes for a better work atmosphere.
Clinical integration
Integrated in Aarhus University Hospital - the largest hospital in Denmark - CoroScience is backed by state-of-the-art facilities and operates as a dynamic nexus where academic inquiry converges with clinical reality. The synergy between researchers and practitioners enables a fluid exchange of insights, accelerating the translation of discoveries into patient care.
TRIAL ARTICLE
International randomized trial on the effect of revascularization or optimal medical therapy of chronic total coronary occlusions with myocardial ischemia - ISCHEMIA-CTO trial – rationale and design
TRIAL REGISTRATION
Clinical Trials
NCT03563417
ISCHEMIA-CTO
To investigate PCI vs. optimal medical therapy of CTO lesions in patients with significant myocardial ischemia and PCI vs. optimal medical therapy of CTO lesions in patients with moderate myocardial ischemia
Trial period
•
2018 - 2028
Status
•
Including
Inclusions
•
1560 Ongoing
Centers
•
15
Countries
•
6
Publications
•
1
OCTAVE
To investigate if routine OCT-guided diagnosis and revascularization yields superior one-year clinical outcome compared with standard angiography-guided diagnosis and revascularization in patients with acute coronary syndrome
Trial period
•
2025 - 2035
Status
•
Initiating
Inclusions
•
3000 Ongoing
Centers
•
50
Countries
•
15
Publications
•
0
MAIN ARTICLE
OCT or Angiography Guidance for PCI in Complex Bifurcation Lesions
TRIAL ARTICLE
Rational and design of the European randomized Optical Coherence Tomography Optimized Bifurcation Event Reduction Trial (OCTOBER)
TRIAL REGISTRATION
Clinical Trials
NCT03171311
OCTOBER
To investigate whether PCI with routine OCT guidance is superior to standard angiography-guided PCI in revascularization of complex lesions located at a coronary bifurcation.
Trial period
•
2017 - 2027
Status
•
Follow-up
Inclusions
•
1201 Complete
Centers
•
38
Countries
•
13
Publications
•
5
FAVOR III
The trial will investigate something something computation of fractional flow reserve (FFR) based on invasive coronary angiographic images and will evaluate something of intermediate coronary stenosis.
Trial period
•
2018 - 2026
Status
•
Follow-up
Inclusions
•
2000 Complete
Centers
•
43
Countries
•
13
Publications
•
3
NOBLE
To investigate Coronary Artery Bypass Grafting Versus Drug Eluting Stent Percutaneous Coronary Angioplasty in the Treatment of Unprotected Left Main Stenosis in a clinical, randomized 5 year follow-up trial.
Trial period
•
2008 - 2025
Status
•
Complete
Inclusions
•
1201 Complete
Centers
•
36
Countries
•
9
Publications
•
6